Status:
UNKNOWN
Geniculate Artery Embolization for the Treatment of Knee Osteoarthritis
Lead Sponsor:
University of Calgary
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
40+ years
Phase:
NA
Brief Summary
Osteoarthritis (OA) is a highly prevalent degenerative joint disease that contributes to chronic pain and disability in approximately 10% of people over the age of 55. With 25% of Canadians expected t...
Eligibility Criteria
Inclusion
- VAS score of at least 50 mm for knee pain
- Pain resistant to at least 3 months of conservative therapy (including medical therapy, physiotherapy, intra-articular cortisone or viscosupplement injection).
- Age \> 40 years
- Radiographs demonstrating knee osteoarthritis on same side as pain
- Patient not a surgical candidate or declines surgical management
Exclusion
- Radiographically severe knee osteoarthritis (Kellgren-Lawrence grade \>2)
- Severe non-knee related lower limb pain with VAS \> 50 mm.
- Local infection and inflammatory arthritis.
- Malignancy
- Previous knee surgery
- Bleeding risk - known hematologic disease increasing risk of bleeding, pre-procedure INR \> 1.4, pre-procedure PTT \> 40 seconds or pre-procedure platelets \< 50,000/uL
- Known chronic renal failure or eGFR \< 45
- ECOG grade \> 2
- Patient weight \> 300 lbs
- Patient unreliable for follow up
Key Trial Info
Start Date :
January 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2024
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT05386797
Start Date
January 1 2023
End Date
June 1 2024
Last Update
December 19 2023
Active Locations (1)
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1
Foothills Hospital
Calgary, Canada