Status:

UNKNOWN

The Effects of Individualized Lung-protective Ventilation With Lung Dynamic Compliance-guided Positive End-expiratory Pressure(PEEP) Titration on Postoperative Pulmonary Complications of Pediatric Video-assisted Thoracoscopic Surgery

Lead Sponsor:

Jiaxiang Chen

Conditions:

Anesthesia

Surgery

Eligibility:

All Genders

1-5 years

Phase:

NA

Brief Summary

This study evaluates the influence of individualized lung-protective ventilation strategy(LPVS) on postoperative pulmonary complications(PPCs) through a randomized controlled trial when children under...

Detailed Description

With the advancement of pediatric thoracic surgery techniques, the age group of children who can receive thoracoscopic surgery is getting younger and younger, and even neonates can accept it. In thora...

Eligibility Criteria

Inclusion

  • Children undergoing elective thoracoscopic pulmonary surgery.
  • Written informed consent.
  • Children under 5 years old (including 5 years old)
  • ASA classification 1-2
  • Respiratory Risk Assessment in Catalan Surgical Patients (ARISCAT) Criteria Low or Moderate Risk

Exclusion

  • Symptoms of upper respiratory tract infection or pulmonary infection in the past 4 weeks, chest X-ray suggests pneumonia
  • Severe circulatory disease
  • Children with bullae
  • Intraoperative arterial blood pressure monitoring cannot be performed
  • Respiratory Risk Assessment in Catalan Surgical Patients (ARISCAT) Criteria Rated High Risk

Key Trial Info

Start Date :

June 10 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2024

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05386901

Start Date

June 10 2022

End Date

October 1 2024

Last Update

October 30 2023

Active Locations (1)

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Shenzhen Children's Hospital

Shenzhen, Guangdong, China, 518038