Status:
COMPLETED
International Registry of Acute Kidney Injury in Cirrhosis: The GLOBAL AKI Project
Lead Sponsor:
Azienda Ospedaliera di Padova
Conditions:
Liver Cirrhosis
Acute Kidney Injury
Eligibility:
All Genders
18+ years
Brief Summary
The aims of this study will be to identify the clinical characteristics, the management and the outcomes of acute kidney injury in patients with cirrhosis worldwide. Specific aims: 1. To establish t...
Detailed Description
Each center will then include patients with cirrhosis who are admitted to the hospital with AKI upon admission or who develop AKI during the hospital stay, and who provide signed informed consent. Ac...
Eligibility Criteria
Inclusion
- a) Patients with cirrhosis admitted to hospital for the treatment of a complication of liver disease (ascites, gastrointestinal bleeding, hepatic encephalopathy, bacterial infections, jaundice, etc)
Exclusion
- Age \< 18 years old;
- Pregnancy;
- Hepatocellular carcinoma outside Milan criteria (i.e., a single lesion \<5 cm or multiple lesions \[maximum of three\], the largest of which measures ≤ 3 cm);
- Extrahepatic malignancy other than non-melanoma skin cancer within last 5 years;
- Previously known severe extrahepatic diseases (e.g., chronic renal failure requiring hemodialysis, severe congestive heart disease \[NYHA class ≥ 3\]; severe chronic obstructive pulmonary disease \[GOLD class ≥ 3\], psychiatric disorders);
- Previous solid organ transplantation;
- HIV infection with CD4 ≤ 250/µL;
- Patients who cannot provide prior informed consent and no legal surrogate decision maker
Key Trial Info
Start Date :
July 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 30 2023
Estimated Enrollment :
1456 Patients enrolled
Trial Details
Trial ID
NCT05387811
Start Date
July 1 2022
End Date
November 30 2023
Last Update
January 30 2024
Active Locations (38)
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1
Indiana University
Indianapolis, Indiana, United States, 46202
2
Ochsner Medical Center
New Orleans, Louisiana, United States, 70121
3
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
4
Baylor University Medical Center
Dallas, Texas, United States, 75246