Status:

COMPLETED

AI Quantitative Coronary Angiography Versus Optical Coherent Tomography Guidance for Coronary Stent Implantation

Lead Sponsor:

Asan Medical Center

Collaborating Sponsors:

Korea Medical Device Development Fund

Medipixel,Inc

Conditions:

Coronary Vessels

Procedure PCI

Eligibility:

All Genders

19+ years

Phase:

NA

Brief Summary

This study is to establish the primary hypothesis thatAI -QCA guided PCI is non-inferior to Optical coherence tomography-guided Percutaneous coronary intervention regarding minimal Stent area by Final...

Detailed Description

1. AI-QCA-assisted DES implantation After coronary angiography, AI-QCA software will be used to determine the lesion length and the reference vessel diameter in real time to determine the appropri...

Eligibility Criteria

Inclusion

  • Men or women at least 19 years of age
  • Patients with typical symptoms or objective evidence of myocardial ischemia and eligible for coronary angioplasty.
  • Subject with severe coronary artery disease undergoing PCI
  • Written informed consent

Exclusion

  • Angiographic exclusion criteria 1) Left main lesion 2) Chronic total occlusion 3)Graft vascular lesion 4) Requiring two-stent techniques for coronary bifurcation lesions 5)Any lesion characteristics resulting in the expected inability to deliver OCT catheter to the lesion ( eg,tortuosity, moderate or severe vessel calcification)
  • Acute or chronic renal dysfunction (Plasma creatinine 2.0mg/dL or more) except patients undergoing dialysis
  • Primary coronary angioplasty in ST-elevation myocardial infarction(within 12-24 hours of symptom onset)
  • Previous PCI with BVS
  • LV dysfunction (LVEF) \< 30%
  • Hypersensitivity to DES and its components or there is a reason for prohibition (everolimus, cobalt, chromium, nickel, platinum, tungsten, acrylic and fluoro polymers)
  • Patients who require surgery requiring discontinuation of antiplatelet drugs within 1 year of the procedure
  • Life expectancy \< 1 year for any disease
  • Pregnancy or breast-feeding
  • Patients unsuitable for enrollment judged by the Investigator

Key Trial Info

Start Date :

October 4 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 2 2024

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT05388357

Start Date

October 4 2022

End Date

October 2 2024

Last Update

October 24 2024

Active Locations (13)

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Page 1 of 4 (13 locations)

1

Sejong General Hospital

Bucheon-si, South Korea

2

Keimyung University Dongsan Medical Center

Daegu, South Korea

3

Kyungpook National University Hospital

Daegu, South Korea

4

GangNeung Asan Hospital

Gangneung, South Korea

AI Quantitative Coronary Angiography Versus Optical Coherent Tomography Guidance for Coronary Stent Implantation | DecenTrialz