Status:

NOT_YET_RECRUITING

A Tailored Psychological Intervention (MITIG.RA) for Managing Fatigue in Rheumatoid Arthritis

Lead Sponsor:

Unidade Local de Saúde de Coimbra, EPE

Conditions:

Rheumatoid Arthritis

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

The objective of this study is to examine the efficacy of the Compassion and Mindfulness Intervention for RA (MITIG.RA), a novel intervention combining different components of Cognitive Behavioural Th...

Detailed Description

Primary aim: to investigate the impact of the program Compassion and Mindfulness Intervention for RA (MITIG.RA) in RA-associated fatigue in comparison to treatment as usual (TAU). Secondary aims: the...

Eligibility Criteria

Inclusion

  • Fulfilling the 1987 ACR or 2010 ACR/EULAR classification criteria for RA;
  • In PGA-near remission: Tender and swollen 28 joint counts and C-reactive protein (CRP) (mg/dl) \< 1, and Patient Global Assessment of disease Activity (PGA \> 1,
  • RAID - fatigue ≥ 3;
  • PESS \< "good"
  • Under stable medication (at least 3 months).

Exclusion

  • Less than 6 years of formal education;
  • Unable to attend zoom meetings unaided;
  • Unable to fulfil self-report questionnaires unaided;
  • Pain-related comorbidities (e.g. fibromyalgia or osteoarthritis)
  • Presence of other comorbid medical conditions that may cause fatigue, such as anaemia (Hb\<10mg/dL), uncontrolled hypothyroidism or cancer;
  • Presence of severe psychological symptoms or disorders (e.g. psychosis, severe depression, substance abuse);
  • Currently ongoing psychological interventions or formal psychiatric treatment;
  • Pregnant patients;
  • Otherwise disabled patients (advanced articular/bone erosion);
  • Refuse to provide informed consent.

Key Trial Info

Start Date :

September 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 30 2025

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT05389189

Start Date

September 1 2024

End Date

September 30 2025

Last Update

February 14 2024

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