Status:

TEMPORARILY_NOT_AVAILABLE

Intermediate-size IND for Treatment of KRAS G12V-mutant Tumors

Lead Sponsor:

Providence Health & Services

Conditions:

KRAS G12V Mutant Advanced Epithelial Cancers

Eligibility:

All Genders

18+ years

Brief Summary

This intermediate-size IND will treat participants with incurable, advanced or metastatic cancer, harboring KRAS G12V mutation and appropriate HLA class II match (HLA-DRB1\*07:01).

Detailed Description

This study will treat two identified patients with metastatic pancreatic adenocarcinoma and metastatic pancreatic cancer who have both been treated with standard of care therapies and found to have di...

Eligibility Criteria

Inclusion

  • Patients with incurable, advanced or metastatic cancer, harboring KRAS G12V mutation, and appropriate HLA class II match (HLA-DRB1\*07:01)

Exclusion

    Key Trial Info

    Start Date :

    Trial Type :

    EXPANDED_ACCESS

    End Date :

    Estimated Enrollment :

    Patients enrolled

    Trial Details

    Trial ID

    NCT05389514

    Last Update

    November 20 2025

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