Status:
UNKNOWN
Treatment for Major Depressive Disorder With Intermittent Theta-burst Stimulation
Lead Sponsor:
Chang Gung Memorial Hospital
Conditions:
Depressive Disorder, Treatment-Resistant
Eligibility:
All Genders
20-70 years
Phase:
NA
Brief Summary
The main purpose of this study is to investigate the two different intermittent Theta Burst (iTBS) repetitive transcranial magnetic stimulation (rTMS), its effectiveness in alleviating depressive symp...
Eligibility Criteria
Inclusion
- The diagnosis of major depressive disorder according to DSM-5
- Total HAM-D17 score of greater than or equal to 18 and Item 3 score less than 4 at screening visit. CGI-S score less than 4.
- Before treatment, patient have to stop antidepressant for at least 1 weeks.
- Capable and willing to provide informed consent.
Exclusion
- Have a concomitant major, unstable medical or neurologic illness :
- Psychiatric disorder: Schizoprenia, Bipolar disorder, Obsessive Compulsive Disorder, Posttraumatic Stress Disorder, substance use disorder.
- Severe brian disease: Brain tumor, encephalitis, brian injury.
- Intracranial implant and other ferromagnetic materials close to the head.
- History of Seizures.
- Cardiac pacemaker.
- Pregnancy.
Key Trial Info
Start Date :
August 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 31 2023
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT05390593
Start Date
August 1 2021
End Date
July 31 2023
Last Update
May 25 2022
Active Locations (1)
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1
ChangGungMH
Kaohsiung City, Taiwan, 833