Status:

COMPLETED

Pathophysiology of Gas Exchange and Time Course Changes in Spontaneously Breathing Patients With Acute Respiratory Failure Due to COVID-19. A Multicenter Prospective Study.

Lead Sponsor:

CHU de Reims

Conditions:

Respiratory Insufficiency

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The pathophysiology of SARS-COV-2 related respiratory disease is still poorly understood, especially in its most severe form called acute respiratory distress syndrome (ARDS). In this case, very few s...

Eligibility Criteria

Inclusion

  • inclusion criteria :
  • Patients with a COVID-19 confirmed infection.
  • Admission in intensive care unit for an acute respiratory failure requiring oxygen flow above 6l/min by facial mask.
  • Presence of an arterial catheter for blood sampling.
  • exclusion criteria :
  • Patients on mechanical ventilation on admission to the ICU.
  • Patients requiring immediate intubation on admission.
  • Patients admitted to the ICU for more than 48 hours at the time of inclusion.
  • Pulmonary embolism diagnosed before admission to the ICU.
  • Minor patients
  • Pregnant women
  • Patients under curatorship or guardianship
  • Persons deprived of liberty by a judicial or administrative decision

Exclusion

    Key Trial Info

    Start Date :

    June 9 2021

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    April 15 2023

    Estimated Enrollment :

    59 Patients enrolled

    Trial Details

    Trial ID

    NCT05392062

    Start Date

    June 9 2021

    End Date

    April 15 2023

    Last Update

    December 13 2024

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Damien JOLLY

    Reims, France