Status:
RECRUITING
Magnetocardiography in the Accurate Identification of Severe Coronary Lesions and Myocardial Necrosis
Lead Sponsor:
Qilu Hospital of Shandong University
Collaborating Sponsors:
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Weifang People's Hospital
Conditions:
Chest Pain, Acute Coronary Syndrome, Myocardial Infarction
Eligibility:
All Genders
18-79 years
Phase:
NA
Brief Summary
Magnetocardiography (MCG) is a promising noninvasive and accurate method for detecting myocardial ischemia. Although progress has been made in this area, there is a lack of studies using up-to-date ex...
Eligibility Criteria
Inclusion
- For healthy volunteers:
- Age 18-79 years old;
- No history of cardiovascular disease (coronary heart disease, structural heart disease, arrhythmia, heart failure, stroke, pulmonary embolism, aortic dissection, etc.), no cardiovascular risk factors (hypertension, diabetes, hyperlipidemia). For people over 65 years old, those with hypertension or hyperlipidemia, but with well-controlled blood pressure and lipid levels, taking no more than 2 drugs, and echocardiography showing no left ventricular hypertrophy, can be included;
- The electrocardiogram is normal, and the cardiac ultrasound is basically normal in the past 1 year (mild valvular regurgitation can be included).
- Sign the informed consent.
Exclusion
- Those who with acute or chronic respiratory diseases;
- Those who with obvious abnormality of liver or kidney function;
- Those who with endocrine diseases such as abnormal thyroid function;
- Those who with anemia or other blood diseases;
- Those who with connective tissue diseases (lupus erythematosus, rheumatoid arthritis, dermatomyositis, polyarteritis nodosa, etc.);
- Those who are obese (BMI\>30kg/cm2) or underweight (BMI\<18kg/cm2);
- Those who with malignant tumors;
- Those who with infectious diseases or infectious diseases;
- Those who with trauma or physical disability;
- Those who with psychological or mental illness such as depression;
- Those who are professional athletes, pregnant or breastfeeding women, alcoholics;
- Those who are unable to perform magnetocardiography examination due to claustrophobia, etc., or those who fail to receive magnetocardiography examination;
- Due to various reasons such as allergy to contrast agents, metal implants in vivo that are prohibited from performing 1.5T MRI (such as prostheses or steel plates implanted in orthopaedics, uterine contraceptive device) and other reasons, those who cannot or fail to cooperate with the corresponding research requirements.
- For chest pain patients who will undergo CAG or CTA:
- Inclusion Criteria:
- Age 18-79 years old;
- Those with chest pain symptoms, diagnosed or highly suspected by the attending doctor or above as stable angina pectoris (SA), unstable angina pectoris (UA), non-ST segment elevation myocardial infarction (NSTEMI), ST segment elevation myocardial infarction (STEMI), and plan to receive CAG or coronary CTA;
- Sign the informed consent.
Key Trial Info
Start Date :
May 30 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2024
Estimated Enrollment :
430 Patients enrolled
Trial Details
Trial ID
NCT05392712
Start Date
May 30 2022
End Date
December 30 2024
Last Update
August 22 2024
Active Locations (1)
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1
Qilu Hospital of Shandong University
Jinan, Shandong, China, 250012