Status:
RECRUITING
Adipose Cellular Kinetics of Lipedema
Lead Sponsor:
Pennington Biomedical Research Center
Collaborating Sponsors:
Lipedema Foundation
Conditions:
Lipedema
Eligibility:
FEMALE
18-45 years
Brief Summary
Lipedema is characterized by an abnormal deposition of adipose tissue, resulting in fluid accumulation, limb enlargement, and pain. Lipedema is often misdiagnosed as simply obesity. A major challenge ...
Eligibility Criteria
Inclusion
- BMI ≤50 kg/m2
- Waist/hip ratio \<0.86 (standing position)
- Clinical diagnosis of lipedema (mostly Stage 3 but Stage 2 will not be excluded)
- Willing to drink deuterated water (2H2O)
Exclusion
- Have major organ disease (heart, kidney, lung, thyroid, liver) or abnormal liver enzymes that represent a problem for study inclusion
- Chronic use of systemic glucocorticoids, atypical anti-psychotic medications, or medications that cause clinically significant changes in weight
- Pregnancy or breastfeeding in the next 3 months
- Partial and/or full hysterectomy (due to estrogen effects on adipogenesis)
- PCOS
- Self-reported positive test for HIV, hepatitis B and hepatitis C
- Smoking or use of tobacco products in the last 6 months
- Any medical, psychiatric or behavioral factors that may interfere with study participation
Key Trial Info
Start Date :
April 7 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT05394467
Start Date
April 7 2022
End Date
December 31 2025
Last Update
March 17 2025
Active Locations (1)
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1
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States, 70808