Status:
COMPLETED
Gingival Crevicular Fluid, Salivary, and Serum Biomarkers Levels in Periodontal Treatment
Lead Sponsor:
Marmara University
Conditions:
Periodontal Health
Periodontitis
Eligibility:
All Genders
30-55 years
Phase:
NA
Brief Summary
The present study aimed to assess the effect of non-surgical periodontal treatment on gingival crevicular fluid (GCF), saliva, and serum IL-26, IL-6, and IL-10 levels in stage III grade B periodontiti...
Detailed Description
Periodontitis is an inflammatory process that can result in tooth loss by destroying teeth-supporting tissues. Interleukin (IL) 26, is one of the recent members of the IL-10 cytokine family. The eleva...
Eligibility Criteria
Inclusion
- systemically healthy and non-smoker individuals
- having ≥20 teeth present (except third molars)
- individuals with periodontally healthy, stage III grade B and C periodontitis diagnoses
Exclusion
- having any diagnosed medical disorders
- usage of antibiotics, non-steroidal anti-inflammatory drugs, and immunosuppressive agents within the past 6 months
- having any non-inflammatory destructive periodontal disease
- non-surgical/surgical periodontal therapy received in the past year
- pregnant/ lactating/ postmenopausal females
Key Trial Info
Start Date :
November 12 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 23 2020
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT05395455
Start Date
November 12 2018
End Date
January 23 2020
Last Update
May 27 2022
Active Locations (1)
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1
Hatice Selin Yıldırım
Istanbul, Turkey (Türkiye)