Status:

RECRUITING

Fecal Immunochemical Test for Post-polypectomy Surveillance to Reduce Unnecessary eNdoscopy

Lead Sponsor:

University of Calgary

Conditions:

Colorectal Neoplasms

Eligibility:

All Genders

18-74 years

Brief Summary

This is an observational study in a clinical setting to estimate the prevalence of advanced colorectal neoplasia (ACN) at colonoscopy in those with a history of low or high risk polyps or a family his...

Detailed Description

Colonoscopy is an effective tool in reducing colorectal cancer (CRC) incidence, however, it is a limited resource that is not without risk. The overall goal of this study is to determine if Fecal Immu...

Eligibility Criteria

Inclusion

  • Men or women age ≤ 74 years of age.
  • At least one risk factor for CRC that would generally lead to colonoscopy screening:
  • Personal history of low risk polyps
  • Personal history of high risk polyps
  • Family history of CRC or polyps

Exclusion

  • Known acromegaly, cystic fibrosis or high risk profession (firefighter)
  • Referred for colonoscopy due to a positive fecal immunochemical test or CT colonography
  • Known or suspected gene carrier for a familial cancer syndrome.
  • Does not meet medical criteria for colonoscopy at the CCSC.
  • Colonoscopy within the previous 30 months
  • Unable to provide written informed consent or complete questionnaires due to language barrier or other reasons.

Key Trial Info

Start Date :

April 15 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

April 15 2027

Estimated Enrollment :

3000 Patients enrolled

Trial Details

Trial ID

NCT05396560

Start Date

April 15 2022

End Date

April 15 2027

Last Update

May 31 2022

Active Locations (1)

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Forzani & Macphail Colon Cancer Screening Centre, University of Calgary

Calgary, Alberta, Canada, T2N 4N1