Status:

COMPLETED

Understanding Individual Differences in Working Memory Training and Transfer in Older Adults

Lead Sponsor:

Northeastern University

Collaborating Sponsors:

University of California, Riverside

National Institute on Aging (NIA)

Conditions:

Cognitive Change

Eligibility:

All Genders

50-85 years

Phase:

NA

Brief Summary

The present study investigates how individual differences in cognitive processing contribute to the efficacy of working memory training programs in an older adult population. In a randomized crossover...

Detailed Description

Three randomized cross-over trials will be conducted to obtain within-subject comparisons of training with enriched (game-like) versions of working memory training tasks compared to basic (non-gamifie...

Eligibility Criteria

Inclusion

  • 50-85 years of age
  • Able to understand and speak English and follow study procedures
  • Does not have a psychological or neurological condition that would prevent being able to give consent to participate
  • Not currently involved in any other cognitive or memory training studies

Exclusion

  • Formal diagnosis of dementia or other neurological disease, including Mild cognitive impairment.
  • A final total score below 17 on Montreal Cognitive Assessment - Blind (telephone) version.
  • Score of 10 or more on the Generalized Anxiety Questionnaire (GAD7; Spitzer et al., 2006, Archives of Internal Medicine), indicating presence of moderate or severe anxiety
  • Score of 9 or more on Geriatric depression scale (GDS15; Yesavage et al., 1982) indicating presence of moderate or severe depression
  • Abnormal visual acuity prohibitive of tablet-based training.
  • Physical handicap (motor or perceptual) that would impede training procedures.
  • Medical illness requiring treatment and/or significant absences during the study timeline.
  • Current evidence or 2-yr history of seizures, focal brain lesion, or head injury with loss of consciousness.
  • Current alcohol consumption exceeds 14 drinks per week.
  • Self-reported illicit drug use.

Key Trial Info

Start Date :

March 17 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 5 2025

Estimated Enrollment :

313 Patients enrolled

Trial Details

Trial ID

NCT05396586

Start Date

March 17 2022

End Date

March 5 2025

Last Update

March 12 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

University of California, Irvine

Irvine, California, United States, 92697

2

University of California, Riverside

Riverside, California, United States, 92521