Status:
RECRUITING
Pharmacokinetic Profile of Lidocaine Given as a Weight-based Infusion for Postoperative Surgical Pain Control
Lead Sponsor:
University of Alberta
Conditions:
Acute Pain
Lidocaine
Eligibility:
All Genders
18+ years
Brief Summary
Study Summary Title Pharmacokinetic profile of lidocaine given as a weight-based infusion for postoperative surgical pain control Short Title Pharmacokinetic profile of lidocaine given as a weight-b...
Detailed Description
1. Background Information 1.1 Investigational Product Lidocaine HCl 2%, perioperative intravenous weight-based infusion over 48 h 1.2 Summary of Literature Given the ongoing opiate epidemic there is...
Eligibility Criteria
Inclusion
- ASA class 1-3. Age 18-40 or \>75. - Scheduled for elective major surgery at the University of Alberta Hospital in which lidocaine infusion would be a good option as part of standard multimodal analgesia care
Exclusion
- Contraindication / History of hypersensitivity to lidocaine or amide local anesthetics
- Inability to give informed consent (illiteracy, \<7th grade education)
- NYHA class III-IV heart disease
- Planned epidural or regional anesthesia technique requiring local anesthetic
Key Trial Info
Start Date :
February 12 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2026
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT05402293
Start Date
February 12 2025
End Date
March 1 2026
Last Update
March 7 2025
Active Locations (1)
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1
University of Alberta
Edmonton, Alberta, Canada, T6G2R3