Status:

TERMINATED

Randomized Trial Comparing Irrisept to Saline Irrigation for Infection Prevention

Lead Sponsor:

Brett D. Crist

Conditions:

Gustilo-Anderson Type III Open Tibia Fracture

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

Early debridement and definitive fixation, at the initial operative setting, historically led to no difference in the infection rates for Gustilo-Anderson type III open tibia fractures. However, Lenar...

Eligibility Criteria

Inclusion

  • Adult, 18 or over
  • Gustilo-Anderson type III open tibia fracture
  • Able to obtain informed consent from patient

Exclusion

  • Minor, under 18
  • Pregnancy
  • Prisoner
  • Allergic to chlorhexidine gluconate
  • Allergic to vancomycin or tobramycin
  • Patient's tibia is unable to accommodate the smallest antibiotic nail
  • Unable to provide informed consent

Key Trial Info

Start Date :

June 21 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 31 2023

Estimated Enrollment :

6 Patients enrolled

Trial Details

Trial ID

NCT05402995

Start Date

June 21 2022

End Date

August 31 2023

Last Update

April 24 2024

Active Locations (1)

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1

University of Missouri Health System

Columbia, Missouri, United States, 65212