Status:
RECRUITING
Comparison of Effectiveness of TissuePatchTM in Preventing Postoperative Pancreatic Fistula
Lead Sponsor:
Xijing Hospital of Digestive Diseases
Conditions:
Pancreatic Fistula
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Postoperative pancreatic fistula is one of the most serious complications after gastric cancer surgery and can lead to surgery-related death. Postoperative pancreatic fistula for gastric cancer often ...
Detailed Description
Gastric cancer is the fifth most common tumor and the fourth most deadly cancer disease in the world. Surgical resection is the recommended method to cure gastric cancer. In recent years, with the con...
Eligibility Criteria
Inclusion
- Histological confirmation of gastric adenocarcinoma
- Stage cT1-4a, N0-3, M0 (according to the 8th AJCC TNM staging system)
- For locally advanced tumors (cT3-4aN+M0), preoperative completion of all three cycles of chemotherapy (SOX)
- 18-75 years old
- No incurable factors such as cancer cell metastasis in other organs
- Written informed consent signed voluntarily
Exclusion
- Assessment of preoperative or intraoperative requiring pancreatic resection
- Gastric cancer-related emergency surgery
- Gastric stump carcinoma
- In cases of distant metastasis discovered during operation, only abdominal exploration or palliative surgery were adopt.
- Uncontrolled seizures, central nervous system diseases or mental disorders
- Uncorrectable coagulation dysfunction
- Severe uncontrolled recurrent infections or other severe uncontrolled concomitant diseases
- Diseases requiring immunosuppressive treatment, such as organ transplantation, SLE, etc
- Other diseases requiring simultaneous surgery
Key Trial Info
Start Date :
August 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2026
Estimated Enrollment :
154 Patients enrolled
Trial Details
Trial ID
NCT05404256
Start Date
August 1 2022
End Date
April 1 2026
Last Update
May 8 2024
Active Locations (1)
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1
Xijing Hospital of Digestive Disease
Xi'an, Shaanxi, China, 710032