Status:
UNKNOWN
Computerized Cognitive Remediation Therapy in Adolescents With a First Psychotic Episode
Lead Sponsor:
Fundació Sant Joan de Déu
Conditions:
Early-onset Schizophrenia
Psychotic Disorders
Eligibility:
All Genders
12-18 years
Phase:
NA
Brief Summary
Cognitive deficits (CD) are considered one of the essential characteristics in psychotic disorders and occur throughout the course of the disease, being a key characteristic in the evolution of the di...
Detailed Description
Cognitive deficits (DC) are considered one of the essential features in psychotic disorders and occur throughout the course of the disease. Recent meta-analyses have shown that cognitive remediation t...
Eligibility Criteria
Inclusion
- 1\) Age between 12-18 years
- 2\) DSM-5 diagnostic criteria for schizophrenia or schizoaffective disorder (F20 or F25, DSM-5) beginning at age 17 or earlier;
- 3\) Clinically and pharmacologically stabilized;
- 3\) No changes in drug treatment for 6 weeks from baseline assessment;
- 4\) Presence of cognitive impairment according to criteria adapted in Penades et al. and following the same criteria in previous studies with similar populations. In this sense, at least one of the following criteria must be present:
- 2 discrepant scores (a score is discrepant when the T scores are 1 DE below the patient's estimated IQ
- Either a score T below 37 in persevering Wisconsin Card Sorting Test (WCST) errors by Heaton et al. (1981).
- 5\) Diagnosis and diagnostic stability verified by a psychiatrist or senior psychologist or member of the research team using the DSM-5 criteria and based on clinical interviews with the patient and his family.
Exclusion
- 1\) Intellectual disability CI estimated equivalent to or \<70);
- 2\) Active substance abuse;
- 3\) Neurological impairment;
- 4\) Have received electro-convulsive therapy in the 6 months prior to treatment;
- 5\) Do not sign informed consent.
Key Trial Info
Start Date :
March 19 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2023
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT05405946
Start Date
March 19 2019
End Date
March 1 2023
Last Update
June 27 2022
Active Locations (1)
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1
Hospital Sant Joan de Deu
Barcelona, Spain, 08950