Status:
RECRUITING
Taiwan Geriatric Study for Dementia Risk Prevention and Cognitive Enhancement by Multi-modal Intervention
Lead Sponsor:
Taipei Medical University Shuang Ho Hospital
Conditions:
Dementia
Eligibility:
All Genders
60-90 years
Phase:
NA
Brief Summary
A 3-arm randomized controlled trial of multi-modal non-pharmacological Intervention for preventing the risk of dementia in Taiwanese geriatric people
Detailed Description
This project proposes an intervention program for dementia prevention based on the Taiwanese model. The investigator(s) will screen the elderly who are not yet demented but are at high risk of dementi...
Eligibility Criteria
Inclusion
- People over 60 without dementia
- Agree to join the study and sign the consent form
- The Modified Rankin Scale (MRS) scores between 0-1 points
- Education level: elementary or higher education (6 years) or can read and write Chinese
- Very early dementia screening scale (AD-8) \< 2, or more than 2 points but without dementia diagnoses after refer to a neurologist.
- Cardiovascular Risk Factors, Aging, and Incidence of Dementia (CAIDE) Risk Score: above 8; diagnosed with mild cognitive impairment (MCI) or subjective cognitive decline (SCD) in the past six months.
Exclusion
- Have been diagnosed with any kind of dementia
- Suspected dementia patients or others who are not suitable to participate in the research assessed by a doctor at the first visit
- Diseases affecting the safety of various interventional activities (such as remaining life less than two years, symptomatic heart/cerebrovascular disease within 6 months, vascular reperfusion or reconstruction-related surgery within one year, etc., malignant tumor within one year)
- Severe blindness, hearing or communication impairment, or other difficulty in cooperating or completing assessments and interventions (especially exercise) in the study
- Severe mental illnesses, including major depression disorder, or major neuromusculoskeletal disorders that are not suitable to join the study.
- Drug or alcohol abuse in the last year
- Overlapping with other interventional trials at the same time which may affect the evaluation results.
Key Trial Info
Start Date :
July 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
380 Patients enrolled
Trial Details
Trial ID
NCT05407857
Start Date
July 1 2022
End Date
December 1 2026
Last Update
October 28 2022
Active Locations (1)
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1
Taipei Medical University-Shuang Ho Hospital
New Taipei City, Taiwan, 235