Status:
ENROLLING_BY_INVITATION
Dietary Sugar Absorptive Phenotype for Prediction of Weight Loss Outcome
Lead Sponsor:
Mayo Clinic
Conditions:
Obese
Healthy
Eligibility:
All Genders
18+ years
Brief Summary
This study is trying to determine whether the success of bariatric surgery can be predicted by evaluating the dietary sugar absorptive characteristics in the small intestine and if there is any gene e...
Eligibility Criteria
Inclusion
- \- Obese patients (BMI ≥ 30) scheduled for BS undergoing standard of care screening EGD, or lean BS-naïve individuals (BMI ≤ 25) subjected to EGD for routine clinical indications as part of standard care.
Exclusion
- Adults unable to consent, including non-English speakers.
- Pregnant women because endoscopy is a risk factor. All patients of childbearing age undergo history as well as urine pregnancy test as a standard of care prior to undergoing endoscopy as the procedure is performed under anesthesia.
- Prisoners.
- Subjects with preexisting conditions (e.g., bleeding at the time of the procedure, suspected perforation during the standard-of-care procedure) will be excluded from the study at the time of the endoscopy.
- Have a contraindication to endoscopy.
- A history of surgery on the stomach or small intestine.
- Type 1 diabetes (clinical diagnosis and/or positive glutamic acid decarboxylase antibodies).
- Using weight loss medications.
- Active malignancy within the last 5 years.
Key Trial Info
Start Date :
July 10 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 1 2026
Estimated Enrollment :
52 Patients enrolled
Trial Details
Trial ID
NCT05408728
Start Date
July 10 2022
End Date
August 1 2026
Last Update
September 10 2025
Active Locations (1)
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1
Mayo Clinic Florida
Jacksonville, Florida, United States, 32224