Status:

UNKNOWN

Impact of Thoracic Epidural Versus Serratus Anterior Plane Block Versus Erector Spinae Plane Block on Incidence of PTPS

Lead Sponsor:

National Cancer Institute, Egypt

Conditions:

Post-thoracotomy Pain Syndrome

Erector Spinae Plane Block

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

The aim of this study is to evaluate the impact of Ultrasound-guided Erector Spinae plane block compared to Ultrasound-guided serratus anterior plane block on the emergence of post-thoracotomy pain sy...

Detailed Description

Lung cancer has the highest incidence of all malignancies worldwide and accounts for approximately 13% of all cancer cases. Lung cancer is still the most common cause of cancer-related deaths, and lun...

Eligibility Criteria

Inclusion

  • Age (18-65) Years
  • Physical status American Society of Anesthesiologists Classification II, III
  • Patients undergoing lobectomy through lateral thoracotomy
  • Body mass index (BMI): (20-40) kg/m2

Exclusion

  • Patient refusal.
  • Age \<18 years or \>65 years
  • Body mass index (BMI) \<20 kg/m2 and \>40 kg/m2
  • Known sensitivity or contraindication to drugs used in the study
  • Contraindication to regional anesthesia e.g. local infection at site of introduction, pre-existing peripheral neuropathies and coagulopathy.
  • Pregnancy.
  • Physical status American Society of Anesthesiologists Classification IV
  • patients on chronic analgesic therapy (daily morphine ≥30 mg or equivalent dose of other opioids or tramadol or any medication for neuropathic pain)
  • patients with a history of drug abuse
  • patients with neuropsychiatric diseases; patients with a history of chronic pain syndromes that may enhance sensitivity to pain, for example, fibromyalgia
  • patients with a history of thoracic surgery through lateral thoracotomy; and patients with recurrent chest malignancies within 3 months.
  • All patients who developed severe intra- or post-operative bleeding or required postoperative mechanical ventilation were also excluded from the study.
  • Thoracic spine disorders or deformity.

Key Trial Info

Start Date :

June 20 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2023

Estimated Enrollment :

111 Patients enrolled

Trial Details

Trial ID

NCT05409144

Start Date

June 20 2022

End Date

April 1 2023

Last Update

June 8 2022

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Impact of Thoracic Epidural Versus Serratus Anterior Plane Block Versus Erector Spinae Plane Block on Incidence of PTPS | DecenTrialz