Status:

UNKNOWN

Comparative Study of Ketamine Added to Bupivacaine in PECS Block Versus Topical Wound Instillation on Post Operative Analgesia in Modified Radical Mastectomy Surgery

Lead Sponsor:

Assiut University

Conditions:

Ketamine, Pecs Block, Topical Wound Instillation , Modefied Radical Mastectomy

Eligibility:

FEMALE

18-65 years

Phase:

EARLY_PHASE1

Brief Summary

Comparative study of ketamine added to bupivacaine in PECS block versus topical wound instillation on post operative analgesia in modified radical mastectomy surgery

Eligibility Criteria

Inclusion

  • \- 1) female patients aged 18 - 60 years, 2) American Society of Anesthesiologists (ASA) class \| , \|\| , \|\|\| 3) With body weight of 50 - 90 kg . 4) female patients diagnosed with cancer breast and scheduled for modified radical mastectomy .
  • 5\) patients not known to be allergic to any of the medications used in the study.

Exclusion

  • \- 1) patients with known allergy to the study drugs . 2) patients with significant cardiac, respiratory, renal or hepatic disease . 3) patients with drug or alcohol abuse . 4) patients with psychiatric illness that would interfere with perception and assessment of pain.
  • 5\) Patients with a history of bleeding diathesis; opioid dependence; sepsis; prior surgery in the supraclavicular, infraclavicular or axillary regions.

Key Trial Info

Start Date :

May 15 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 15 2023

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05410158

Start Date

May 15 2023

End Date

August 15 2023

Last Update

May 16 2023

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