Status:

TERMINATED

Family-Based Behavioral Treatment for Childhood Survivors of Acute Lymphoblastic Leukemia

Lead Sponsor:

Washington University School of Medicine

Conditions:

Acute Lymphoblastic Leukemia

Eligibility:

All Genders

5+ years

Phase:

NA

Brief Summary

A single-arm, non-randomized four-month trial of the adapted family-based behavioral weight loss treatment (FBT) intervention will be conducted to evaluate its acceptability, feasibility, and prelimin...

Eligibility Criteria

Inclusion

  • English-speaking caregiver-child dyads
  • Children must be between ages of 5-18
  • Child must be overweight or obese (defined as a BMI greater than the 85th percentile for their age and sex)
  • Child must have been diagnosed with ALL
  • Child must have completed their final cancer treatment and currently be in remission
  • Only children and adolescents who have not yet graduated from high school and are living at home with their caregiver at least 50% of the time will be invited to enroll
  • Participating caregivers and children must be able to perform some level of exercise

Exclusion

  • Children who are wards of the state
  • Caregivers and/or children who are taking a weight altering medication without being at current dosage for at least six months and weight stable for at least three months
  • Caregivers and/or children who are actively involved in another intensive weight loss program
  • Caregivers and/or children who have undergone weight loss surgery within the last two years and/or who are still losing weight
  • Caregivers and/or children with certain diagnosed psychiatric conditions (e.g., history of/active eating disorder, developmental delays/intellectual disabilities such as Down's syndrome and severe presentations of autism spectrum disorder, active suicidal ideation, psychotic symptoms, manic or hypomanic episodes, severe substance use disorder) that would interfere with their ability to participate
  • Caregivers and/or children with certain chronic medical conditions (e.g., type 1 diabetes, muscular dystrophy) for whom participation may be contraindicated

Key Trial Info

Start Date :

July 22 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 26 2024

Estimated Enrollment :

17 Patients enrolled

Trial Details

Trial ID

NCT05410574

Start Date

July 22 2022

End Date

March 26 2024

Last Update

May 3 2024

Active Locations (1)

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1

Washington University School of Medicine

St Louis, Missouri, United States, 63110