Status:
RECRUITING
Study of Role of Blood Microvescicles and Exosomes in Patients With Graft Occlusion After Aortocoronary Bypass Surgery
Lead Sponsor:
Maria Cecilia Hospital
Conditions:
Coronary Artery Bypass Surgery
Eligibility:
All Genders
40-80 years
Brief Summary
Coronary artery bypass graft (CABG) surgery is still the standard treatment of coronary revascularization for patients with severe coronary artery disease (CAD). Graft patency, together with completen...
Detailed Description
Circulating microvesicles (MVs) have received increasing attention during the last years as novel players in cardiovascular disease. MVs are small membrane vesicles involved in cell-to-cell communicat...
Eligibility Criteria
Inclusion
- between the ages of 40 and 80
- Ejection fraction\> 30%
- coronary artery bypass surgery
- informed consent
- Willingness to carry out the follow-up visits and the assessments required by the protocol
Exclusion
- emergency intervention
- changes in liver or kidney function
- changes in coagulation factors
- associated interventions (valve replacement, carotid endarterectomy)
Key Trial Info
Start Date :
June 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2025
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT05411445
Start Date
June 1 2022
End Date
September 1 2025
Last Update
August 28 2024
Active Locations (1)
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1
MCH
Cotignola, Ravenna, Italy, 48033