Status:
COMPLETED
a Pilot Study of Lidocaine Infusion for Postoperative Analgesia in Elderly Patients With Colorectal Cancer Surgery
Lead Sponsor:
West China Hospital
Conditions:
Colorectal Cancer
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
patients who meet the enrollment criteria will be randomized 1:1:1:1 to the different doses of lidocaine or the placebo group. In the lidocaine groups, at the beginning of surgery, lidocaine 0.5mg/kg,...
Detailed Description
patients who meet the enrollment criteria will be randomized 1:1:1:1 to the different doses of lidocaine or the placebo group. In the lidocaine groups, at the beginning of surgery, lidocaine 0.5mg/kg,...
Eligibility Criteria
Inclusion
- Age over 60 years old；
- American Society Anesthesiologygist(ASA)I\~III；
- Patients scheduled for colorectal cancer surgery；
- The surgery takes more than two hours
Exclusion
- BMI≥30kg/㎡or BMI≤18kg/㎡；
- Combined with other organ malignancies；
- Chronic opioid use, substance abuse, contraindication to the use or incompatibility of any drug in the study；
- Patients with liver and kidney insufficiency and chronic pain at the surgical site；
- Accompanied by severe heart disease (such as severe atrioventricular block, severe heart failure, etc.)；
- A history of uncontrolled seizures or acute porphyria；
- Patients who have taken other experimental drugs or participated in or are participating in other clinical trials within 3 months before being enrolled in the study
Key Trial Info
Start Date :
June 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 25 2022
Estimated Enrollment :
220 Patients enrolled
Trial Details
Trial ID
NCT05412576
Start Date
June 1 2021
End Date
December 25 2022
Last Update
March 13 2024
Active Locations (1)
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1
West China Hospital
Chengdu, Sichuan, China, 610041