Status:

RECRUITING

Effect of Meal Composition and Timing Modification on Glucose Metabolism, Body Temperature and Sleep

Lead Sponsor:

Stanford University

Conditions:

PreDiabetes

Type 2 Diabetes

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of our study is to understand the impact of different meal timing alterations on blood sugars, metabolism, microbiome and sleep physiology in people with prediabetes and diabetes; and to s...

Detailed Description

Pilot data points to an effect of the time between waking up and first meal is important in blood glucose management through the rest of the day. The investigators are interested in understanding the ...

Eligibility Criteria

Inclusion

  • Be 18 years of age or older;
  • Not be pregnant, if female;
  • Be generally healthy (with no apparent symptoms at the time of enrollment)
  • Patients with prediabetes or diet- controlled or type 2 diabetes or controlled with metformin, will also be allowed to participate.
  • Be willing to provide written informed consent for all study procedures.

Exclusion

  • major organ disease
  • pregnant/lactating
  • diabetes medications except for metformin
  • malabsorptive disorders like celiac sprue
  • heavy alcohol use
  • use of weight loss medications or specific diets
  • weight change \>2 Kg in the last month
  • history of bariatric surgery
  • Any medical condition that physicians believe would interfere with study participation or evaluation of results
  • Mental incapacity and/or cognitive impairment on the part of the patient that would preclude adequate understanding of, or cooperation with, the study protocol.

Key Trial Info

Start Date :

February 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT05413928

Start Date

February 1 2023

End Date

December 1 2025

Last Update

December 2 2024

Active Locations (1)

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Stanford University

Stanford, California, United States, 94304