Status:

COMPLETED

Effectiveness and Safety of 0.5% Moxifloxacin Hydrochloride Ophthalmic Solution in Perioperative Sterilization in Patients Undergoing Ophthalmic Surgery

Lead Sponsor:

Novartis Pharmaceuticals

Conditions:

Post Operative Endophthalmitis

Eligibility:

All Genders

18-100 years

Brief Summary

This is a non-interventional, uncontrolled, prospective, multicenter, post marketing surveillance study.

Detailed Description

The study treatment i.e., 0.5% Moxifloxacin hydrochloride ophthalmic solution will be prescribed as per approved label; the assignment of the patient to the therapy will be decided within the current ...

Eligibility Criteria

Inclusion

  • Male or female patients \> 18 years of age, who have been prescribed 0.5% Moxifloxacin drops preoperatively and postoperatively for 2 weeks after ocular Surgery
  • Patient or legally acceptable representative (LAR) willing to voluntarily provide signed informed consent for participation in the study

Exclusion

  • Patients with known history of hypersensitivity to fluoroquinolones
  • Patients with history of serious underlying ocular or systemic disease or complication before surgery
  • Patients diagnosed with an extraocular bacterial, viral, fungal infection prior to surgery
  • Patients who have been administered other topical antibacterial agents within 24 hours of Moxifloxacin administration or systemic antibacterial agents within 72 hours of Moxifloxacin administration
  • Patients who have planned to undergo cataract surgery in both eyes on same day
  • Patients who have participated in another clinical study within 30 days prior to the start of this study
  • Pregnant women/lactating mothers/ women suspected to be pregnant

Key Trial Info

Start Date :

January 27 2024

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 1 2024

Estimated Enrollment :

102 Patients enrolled

Trial Details

Trial ID

NCT05413980

Start Date

January 27 2024

End Date

April 1 2024

Last Update

May 9 2024

Active Locations (9)

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Page 1 of 3 (9 locations)

1

Novartis Investigative Site

Ahmedabad, Gujarat, India, 380016

2

Novartis Investigative Site

Ahmedabad, Gujarat, India, 380052

3

Novartis Investigative Site

Kochi, Kerala, India, 682041

4

Novartis Investigative Site

Nagpur, Maharashtra, India, 441108