Status:
UNKNOWN
Effects of Vasopressors on Cerebral Hemodynamics in Patients With Carotid Endarterectomy (MRI Part)
Lead Sponsor:
Beijing Tiantan Hospital
Conditions:
Carotid Endarterectomy
Eligibility:
All Genders
40-80 years
Phase:
NA
Brief Summary
This study was a single-center, exploratory, randomized controlled trial. First, the effects of ephedrine, phenylephrine, or norepinephrine on cerebral blood flow hemodynamics in CEA patients were eva...
Detailed Description
Carotid endarterectomy is a procedure used to remove plaque from the common and internal carotid arteries and improve cerebral perfusion. Clinical studies have demonstrated the effectiveness of this p...
Eligibility Criteria
Inclusion
- age 40-80 years.
- elective carotid endarterectomy.
- Signed informed consent
Exclusion
- ASA classification IV - VI.
- renal failure (estimated glomerular filtration rate less than 60 ml/min.m2).
- cardiac arrhythmias.
- Allergy to ephedrine, phenylephrine or norepinephrine, gadobutrol.
- patients with preoperative TCD suggesting poor temporal window signal.
- patients with severe carotid artery stenosis with no flow signal detected by TCD
- Patients with tandem lesions of carotid artery stenosis
Key Trial Info
Start Date :
September 30 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05414877
Start Date
September 30 2023
End Date
December 31 2024
Last Update
August 24 2023
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.