Status:

WITHDRAWN

A Study of Participants Undergoing Radial Head Replacement Using the DePuy Synthes Radial Head Replacement System for Partial Replacement of the Elbow Joint

Lead Sponsor:

DePuy Synthes Products, Inc.

Conditions:

Radial Head Fractures

Eligibility:

All Genders

22+ years

Brief Summary

The purpose of this study is to establish survivorship defined by the cumulative incidence of revision over the first 6 months post-implantation.

Eligibility Criteria

Inclusion

  • Male or female - skeletally mature adult (aged 22 or older)
  • Participant, who in the opinion of the Investigator, is able to understand the purpose of the study and is willing to return for all the required post-operative standard of care follow-up visits and have their data collected
  • Participant who is willing to give voluntary, written informed consent to participate in this clinical investigation and authorize the transfer of his/her information to the Sponsor
  • Any one of below:
  • Primary replacement after fracture of the radial head
  • Participant needing a partial radial head replacement for degenerative or post-traumatic conditions presenting pain, crepitation, and decreased motion at the radio-humeral and/or proximal radio-ulnar joint with: i) joint destruction and/or subluxation visible on x-ray and/or ii. resistance to conservative treatment
  • Symptomatic sequelae after radial head resection
  • Revision following failed radial head arthroplasty

Exclusion

  • Dislocations of radius on ulna that would not allow a radio-humeral articulation
  • Rheumatoid arthritis
  • Infection, sepsis, and osteomyelitis
  • Uncooperative participant or participant with neurologic disorders who is incapable of following directions, osteoporosis, metabolic disorders which may impair bone formation, osteomalacia, distant foci of infections which may spread to the implant site, rapid joint destruction, marked bone loss or bone resorption apparent on roentgenogram
  • Participants with limited life expectancy due to significant medical co-morbidity
  • Presence of major vascular or major nerve injury (radial, ulnar, medial, musculocutaneous)
  • Women who are pregnant or lactating
  • Unable to comply with study requirements example, with maintaining follow-up
  • Individuals currently involved in any personal injury litigation, medical-legal or worker's compensation claims
  • Individuals that have participated in a clinical investigation with an investigational product (drug or device) in the last three months
  • Demented or unable to provide informed consent
  • Individuals, in the opinion of the Investigator, who are drug or alcohol abusers or have psychological disorders that could affect their ability to complete participant reported questionnaires or be compliant with follow-up requirements

Key Trial Info

Start Date :

March 31 2023

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 31 2030

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT05415592

Start Date

March 31 2023

End Date

March 31 2030

Last Update

February 16 2023

Active Locations (4)

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Page 1 of 1 (4 locations)

1

MetroHealth Medical Center

Cleveland, Ohio, United States, 44109

2

Slocum Research & Education Foundation

Eugene, Oregon, United States, 97401

3

Inova Orthopaedics - Fairfax

Falls Church, Virginia, United States, 22042

4

Glasgow Royal Infirmary (NHS Greater Glasgow & Clyde)

Glasgow, United Kingdom, G40SF