Status:

UNKNOWN

Comparing Conventional Grid Laser Photocoagulation and Subthreshold Micropulse Laser in Diabetic Macular Edema Using OCT Angiography

Lead Sponsor:

Chinese University of Hong Kong

Conditions:

Diabetic Macular Edema

Eligibility:

All Genders

18+ years

Brief Summary

The prevalence of diabetes mellitus has increased significantly in Hong Kong for the past decade \[1\]. Diabetic macular edema is one of the most common causes of vision loss in patients suffering fro...

Detailed Description

Laser photocoagulation was previously a mainstay treatment for DME before the introduction of anti-vascular endothelial growth factor (anti-VEGF) agents injection. Vascular endothelial growth factor (...

Eligibility Criteria

Inclusion

  • Patients with best-corrected visual acuity better than 20/200 (checked with refraction test)
  • Patients with clinically significant diabetic macular edema (DME) who have not received any treatment within 6 months
  • Patients with central retinal thickness equal / above to around 400 um
  • Patients who are able to have regular visits after laser treatment for at least 6 months

Exclusion

  • Children under the age of 18
  • Patients with proliferative diabetic retinopathy
  • Patients with co-existing retinal or macular disease, including epiretinal membrane and vitreomacular traction
  • Patients with previous history of laser photocoagulation, anti-VEGF injection, intravitreal steroid injection, vitreoretinal or cataract surgery within a period of 6 months
  • Patients with history of uveitis
  • Patients who are unfit or for capturing of OCT-A images
  • Patients with significant media opacity that may interfere with fundal examination and the acquisition of high quality OCT-A images
  • Patients who are unable to give informed consent to enter the study
  • uncooperative

Key Trial Info

Start Date :

June 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2022

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT05416099

Start Date

June 1 2022

End Date

December 1 2022

Last Update

June 13 2022

Active Locations (1)

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1

chinese university of Hong kong

Hong Kong, China