Status:

UNKNOWN

Exendin PET/CT for Imaging of Paragangliomas

Lead Sponsor:

Radboud University Medical Center

Conditions:

Paraganglioma

Eligibility:

All Genders

18+ years

Brief Summary

Functional imaging of paragangliomas (PGLs) is not unequivocal. Existing functional imaging modalities show good but variable results in PGLs, warranting the search for additional molecular imaging ta...

Detailed Description

Rationale: Functional imaging of paragangliomas (PGLs) is not unequivocal. Existing functional imaging modalities show good but variable results in PGLs, warranting the search for additional molecula...

Eligibility Criteria

Inclusion

  • Proven sympathetic PGL with a single tumor detected using standard diagnostic imaging
  • No evidence of metastatic disease
  • CT, SSTR PET/CT and 18F-FDG PET/CT performed (golden standard diagnostic imaging)
  • Scheduled for surgery
  • Able to sign informed consent

Exclusion

  • Breast feeding
  • Pregnancy or the wish to become pregnant within 1 month
  • Calculated creatinine clearance below 40ml/min
  • Evidence of other malignancy than PGL in conventional imaging (suspicious liver, bone and lung lesions)
  • Age \< 18 years
  • Not able to sign informed consent

Key Trial Info

Start Date :

June 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2024

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT05418907

Start Date

June 1 2022

End Date

December 1 2024

Last Update

December 8 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Radboud University Medical Center

Nijmegen, Netherlands, 6500 HB

Exendin PET/CT for Imaging of Paragangliomas | DecenTrialz