Status:
RECRUITING
Audio-vestibular Evaluation of Children and Young Adults With Osteogenesis Imperfecta
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
URC-CIC Paris Descartes Necker Cochin
Conditions:
Osteogenesis Imperfecta
Eligibility:
All Genders
12-20 years
Brief Summary
The aim is to determine whether vestibular deficits are present in OI, then to establish whether a correlation exists between genetic type, severity of OI and audiovestibular phenotype. OI patients ag...
Detailed Description
Osteogenesis Imperfecta (OI), or Lobstein's disease, is a form of congenital osteoporosis, with a prevalence between 1/10,000 and 1/20,000 in France. As of 1979, four phenotypes have been described ac...
Eligibility Criteria
Inclusion
- Patients between the ages of 12-20 years at the time of inclusion
- Diagnosis of Osteogenesis Imperfecta of any type
- Currently followed by a physician at the CRMR OI
- Information and non-opposition of major patients, holders of parental authority and minor patients to participate in the study
Exclusion
- Patients with hearing loss of alternate origin e.g. Cochlear nerve deficiency, atresia, etc.
- Neurological or developmental deficits limiting participation
- Cervico-occipital instability e.g. Chiari's malformation
- Limitations in mobility of the spine e.g. scoliosis, spinal fractural fusion
- Ophthalmologic pathologies e.g. strabism or severe refraction disorder
- Patients under AME (State Medical Aid)
- Protected adult patients, adults unable to express their consent, pregnant or breastfeeding women
Key Trial Info
Start Date :
December 22 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 22 2027
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT05419960
Start Date
December 22 2022
End Date
December 22 2027
Last Update
September 12 2025
Active Locations (1)
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1
Hôpital Necker-Enfants Malades
Paris, France, 75015