Status:
UNKNOWN
Post-prandial Glycaemic Controlling Effects of BSG in Singapore Adults With Metabolic Syndrome
Lead Sponsor:
National University of Singapore
Collaborating Sponsors:
Ministry of Education, Singapore
Conditions:
Metabolic Syndrome
Diabetes
Eligibility:
All Genders
35-85 years
Phase:
NA
Brief Summary
The purpose of this study is to assess the glycaemic controlling effects of BSG and bio-transformed BSG-containing biscuits in Singapore adults with MetS. The investigators hypothesized that consumpti...
Detailed Description
This is a double-blind, randomised, crossover experiment. During the 3-week, 19 subjects will participate in a 3 meal tolerance test (MTT). During each MTT session, all subjects are required to consum...
Eligibility Criteria
Inclusion
- Male and female participants, aged 35-85 years old
- English-literate and able to give informed consent in English
- Willing to follow the study procedures
- Meet any 3 of the 5 following NCEP-ATP III MetS criteria: waist circumference \> 102 cm (male), \> 88 cm (female) (For Asian population: Waist circumference \> 90 cm (male), \> 80 cm (female)); fasting glucose concentration ≥ 100 mg/dL or on medication; triglyceride ≥ 150 mg/dL or on medication; high density lipoprotein cholesterol (HDL) \< 40 mg/dL (male), \< 50 mg/dL (female); systolic or diastolic blood pressure \> 130/85 mmHg or on medication);
Exclusion
- Significant change in weight (≥ 3 kg body weight) during the past 3 months
- Allergy to barley, wheat, corn, egg, or other ingredients found inside the biscuits.
- Acute illness at the study baseline
- Exercising vigorously\* over the past 3 months. \*Defined as having \> 6 metabolic equivalents of exercise daily; approximately 20 mins of moderate intensity exercise (e.g. slow jogging) a day
- Following any restricted diet (e.g. vegetarian)
- Smoking
- Have a daily intake of more than 2 alcoholic drinks per day
- Taking dietary supplements or food which may impact the outcome of interests (e.g. fermented foods, probiotic supplement etc.)
- Consumption of antibiotics over past 3 months.
- Pregnant, lactating, or planning pregnancy in the next 6 months
- Insufficient venous access to allow the blood collection
- Prescribed and taking antihypertensive/cholesterol-lowering/ type-2 diabetic medication which started less than 3 years prior to the intervention participation
- High current intake of fibre\* from brown rice or wholemeal products. \*High, moderate or low intake taken as ≥ 6 servings, 4 - 5 servings, and ≤ 3 servings daily respectively based on My Healthy Plate guidelines
- High current intake of fibre\* from vegetables. \* High, moderate or low intake taken as ≥ 2 servings, 2 servings, and ≤ 1 serving respectively based on My Healthy Plate guidelines
Key Trial Info
Start Date :
June 29 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2024
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT05421780
Start Date
June 29 2022
End Date
July 1 2024
Last Update
November 9 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Yujing Xu
Singapore, Singapore, 117543