Status:
UNKNOWN
Ascitic Fluid Calprotectin as an Accurate Diagnostic Marker for Spontaneous Bacterial Peritonitis
Lead Sponsor:
Sohag University
Conditions:
Spontaneous Bacterial Peritonitis
Eligibility:
All Genders
Phase:
NA
Brief Summary
Spontaneous bacterial peritonitis (SBP) is an infection of the ascitic fluid in patients with liver cirrhosis and portal hypertension. There is no obvious surgical cause as perforation or intraabdomin...
Eligibility Criteria
Inclusion
- \-
- The patients were divided into two groups:
- Non-SBP group: it included 25 patients with cirrhotic ascites without clinical or laboratory evidence of SBP.
- SBP group: it included 25 patients with cirrhotic ascites with SBP. They were diagnosed by positive ascitic fluid bacterial culture, an increase in PMNLs count in ascites (\>250 cells/mm3) and without any intra-abdominal source of infection.
Exclusion
- (1) Cirrhotic patients with and without SBP receiving antibiotics in last 1 week.
- (2) Recent abdominal surgery (\<3 months). (3) abdominal malignancy \[hepatocellular carcinoma (HCC), colorectal carcinoma, gastric carcinoma, pancreatic carcinoma, cholangiocarcinoma\].
- (4) Intra-abdominal infected lesions, such as abscess, appendicitis, cholecystitis, and pancreatitis.
- (5) History of inflammatory bowel disease (Crohn's disease, ulcerative colitis).
- (6) patients with heart failure (HF), hematological, and autoimmune disorders were excluded.
Key Trial Info
Start Date :
June 10 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2022
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT05422118
Start Date
June 10 2022
End Date
December 1 2022
Last Update
August 12 2022
Active Locations (1)
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1
Sohag University Hospital
Sohag, Egypt