Status:

UNKNOWN

HEParin Antagonisation in Transcatheter Aortic Valve Implantation

Lead Sponsor:

Deutsches Herzzentrum Muenchen

Conditions:

Aortic Valve Stenosis

Transcatheter Aortic Valve Implantation

Eligibility:

All Genders

18+ years

Brief Summary

Unfractioned heparin is usually given in a defined dosage during transfemoral TAVI. Activated Clotting Time (ACT) is usually used to measure the heparin effect. ACT-analysis is easy to perform at the ...

Eligibility Criteria

Inclusion

  • Severe aortic valve Stenosis
  • transfemoral TAVI as best therapy option
  • unfractioned heparin for periprocedural anticoagulation

Exclusion

  • known hypersensitivity /allergy to unfractioned heparin or protamine
  • acute systemic infection
  • pre procedural started and ongoing intravenous therapy with unfractioned heparin
  • severe periprocedural adverse event with the need for emergency surgery (with or with our CPB)
  • refusal of the patient to participate

Key Trial Info

Start Date :

July 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

April 1 2023

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT05422170

Start Date

July 1 2022

End Date

April 1 2023

Last Update

July 5 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Deutsches Herzzentrum München des Freistaates Bayern, Technische Universität München

Munich, Bavaria, Germany, D80636