Status:

ACTIVE_NOT_RECRUITING

Rebreathing-induced Hypoxia and Glucose Levels

Lead Sponsor:

University of Texas at Austin

Conditions:

Hypoxemia

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

The aim of this research project is to determine the effect of repeated maximal voluntary apneas on glucose uptake during an oral glucose tolerance test in healthy individuals, individuals with predia...

Detailed Description

It is predicted that 1 in 3 adults will develop diabetes by 2050, implying that a large percentage of the population will become at high risk for cardiovascular disease, the most common cause of death...

Eligibility Criteria

Inclusion

  • Men and women aged 18 to 80 years old

Exclusion

  • Have uncontrolled stage 2 hypertension (˃140/90 mmHg)
  • Are smokers
  • Are pregnant
  • Have a history of cardiovascular disease or indication of cardiovascular disease such as myocardial infarction, left ventricular hypertrophy, ischemic heart disease (or prior ischemia), stroke, and/or other vascular disease
  • Have a history of lung disease
  • Are taking insulin or more than one antihypertensive medication
  • Have poorly controlled diabetes: HbA1c levels ˃ 9%
  • Have been previously diagnosed with diabetic complications (nephropathy, neuropathy, retinopathy) by their family doctor

Key Trial Info

Start Date :

October 21 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 30 2025

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT05422430

Start Date

October 21 2021

End Date

April 30 2025

Last Update

March 25 2025

Active Locations (1)

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1

The Unviersity of Texas at Austin

Austin, Texas, United States, 78712