Status:

UNKNOWN

ARMA (Antireflux Mucosa Ablation) in Patients With Chronic Refractory Reflux Disease

Lead Sponsor:

Klinikum Garmisch-Patenkirchen

Conditions:

Gastro-esophageal Reflux

Reflux, Gastroesophageal

Eligibility:

All Genders

18-85 years

Phase:

NA

Brief Summary

Pilot study of the possible clinical response to anti reflux mucosal ablation in patients with chronic refractory reflux disease

Detailed Description

Prospective, non-controlled, monocentric pilot study in patients with therapy-refractory reflux symptoms under proton pump inhibitor (PPI) therapy or intolerance of the necessary therapy or rapid recu...

Eligibility Criteria

Inclusion

  • typical reflux symptoms more than 2x per week during PPI therapy more than 6 month
  • proof of gastro-esophageal reflux in pH metry oder pH/Impedance measurement

Exclusion

  • age \< 18 y
  • primary motility disorder of the esophagus
  • hiatal hernia \> 3 cm
  • Hill classification \> III
  • pregnancy
  • coagulation disorder
  • mandatory intake of oral anticoagulation drugs

Key Trial Info

Start Date :

July 14 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 31 2023

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT05425771

Start Date

July 14 2022

End Date

May 31 2023

Last Update

July 14 2022

Active Locations (1)

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Klinikum Garmisch-Partenkirchen

Garmisch-Partenkirchen, Bavaria, Germany, 82467