Status:
COMPLETED
Effect of Mechanical Loading on vBMD and Geometry in Patients With Primary Hyperparathyroidism
Lead Sponsor:
EFSTATHIOS CHRONOPOULOS
Conditions:
Primary Hyperparathyroidism
Eligibility:
FEMALE
Brief Summary
In this study we aimed to evaluate the effect of primary hyperparathyroidism (PHPT) on bone geometry simultaneously at the tibia and the radius, peripheral bone sites with similar structure but subjec...
Detailed Description
Postmenopausal women with primary hyperparathyroidism will be included in the study. The diagnosis of primary hyperparathyroidism is based on the high levels of parathyroid hormone and calcium. Postm...
Eligibility Criteria
Inclusion
- Caucasian postmenopausal women with PHPT
Exclusion
- Chronic kidney disease (eGFR\< 60 ml/min/1.73m2), Liver disease Malabsorption syndromes Rheumatic disease Women under medication that could affect aBMD or vBMD measurements, PTH, and /or calcium levels (lithium, thiazide/loop diuretics, estrogen, SERMS, denosumab, bisphosphonates) and corticosteroids
Key Trial Info
Start Date :
January 5 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 8 2020
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT05426512
Start Date
January 5 2016
End Date
December 8 2020
Last Update
June 22 2022
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