Status:

UNKNOWN

Explore the Advantages of Remimazolam Used on Gastroscopy

Lead Sponsor:

Sichuan Provincial People's Hospital

Conditions:

Induction of Anesthesia

Eligibility:

All Genders

18-80 years

Phase:

PHASE4

Brief Summary

There are many different types of intravenous anesthetics used in gastroscopy, but each type of drug has its advantages and disadvantages,remimazolam is a novel ultra-short-acting benzodiazepine with ...

Detailed Description

Sedation for gastroscopy is still a topic of debate in the global anesthesia and gastroenterology communities, and the sedation protocols of anesthesiologists and endoscopists vary widely. There are m...

Eligibility Criteria

Inclusion

  • Patients who are to undergo painless gastroscopy
  • Patients aged 18 - 80 years, regardless of gender
  • 18 \< BMI \< 30 kg/m2.
  • American Society of Anesthesiologists (ASA) classification of I-III.

Exclusion

  • Preoperative hypertensive patients \>180/110 mm Hg or hypotensive patients \<80/50 mm Hg.
  • Heart rate \<50 beats/min.
  • A history of acute inflammation of the respiratory tract that has not been cured within 2 weeks; severe metabolic diseases of the heart, brain, lungs, liver, kidneys and diabetes mellitus; previous heart attack, severe myocardial, ischemia, severe atrioventricular block
  • Those who may have or have had a difficult airway or a history of recovery from abnormal surgical anesthesia
  • Patients with significant electrolyte disturbances such as hyperkalemia
  • Patients with a history of long-term use of immunosuppressive agents such as hormones or adrenal cortical suppression
  • Patients with known allergy to emulsions and opioids
  • Those with combined use of other sedative and analgesic drugs within the preoperative period (including injections, oral and use of related proprietary Chinese medicines)
  • Those suspected of abusing narcotic analgesics or sedatives
  • Those who have neuromuscular system diseases, mental diseases, etc. who do not cooperate and cannot communicate.

Key Trial Info

Start Date :

June 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2022

Estimated Enrollment :

287 Patients enrolled

Trial Details

Trial ID

NCT05429086

Start Date

June 1 2022

End Date

August 1 2022

Last Update

June 23 2022

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