Status:
COMPLETED
Global Warming Impact of Nitrous Oxide
Lead Sponsor:
Sir Ganga Ram Hospital
Conditions:
Global Warming Effect of Nitrous Oxide
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
Environmental hazards of human activity are a topic of present day world, global warming being one of the leading concerns. Gases that contribute to this are greenhouse gases. Nitrous oxide (N2O) is a...
Detailed Description
Earliest use of nitrous oxide (N2O) in medical practice dates back to 1884. It aimed at providing analgesia during surgical procedure. Over the years the N2O use for anaesthesia evolved with the knowl...
Eligibility Criteria
Inclusion
- Age 18-65 years
- ASA physical status I and II
- Patients undergoing elective non-laparoscopic surgeries of minimum 1 hour duration without use of adjuvant central neuraxial or peripheral nerve block under general anaesthesia
Exclusion
- Failure to obtain consent
- Neurological disorders (previous neurosurgery , psychiatric disorders, autonomic system disorders - orthostatic hypotension, transient ischemic attacks )
- Cardiovascular disorders (uncontrolled hypertension, A-V block, sinus bradycardia, congenital heart disease, reduced LV compliance and diastolic dysfunction)
- Hepatorenal insufficiency
- Uncontrolled endocrine disorders (diabetes mellitus, hypothyroidism, hyperthyroidism)
- Electrolyte disturbances (hyponatremia, hypernatremia)
- Pulmonary dysfunction (restrictive /obstructive lung disease)
- Acute /chronic drug dependence /substance abuse
- Closed cavity surgeries (middle ear surgeries, eye surgeries)
- Previous h/o PONV
Key Trial Info
Start Date :
June 29 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 22 2023
Estimated Enrollment :
102 Patients enrolled
Trial Details
Trial ID
NCT05430750
Start Date
June 29 2022
End Date
April 22 2023
Last Update
August 9 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Sir Ganga Ram Hospital
New Delhi, National Capital Territory of Delhi, India, 110060