Status:

COMPLETED

Study of ATI-1777 in Patients 12 to 65 Years Old With Mild to Severe Atopic Dermatitis

Lead Sponsor:

Aclaris Therapeutics, Inc.

Conditions:

Atopic Dermatitis

Eligibility:

All Genders

12-65 years

Phase:

PHASE2

Brief Summary

This is a Phase 2b study to determine the safety, tolerability, pharmacokinetic (PK), and efficacy of ATI-1777 in patients 12 to 65 years old with mild to severe Atopic Dermatitis. Eligible participan...

Eligibility Criteria

Inclusion

  • Able to comprehend and willing to sign the IRB approved ICF/assent prior to administration of study-related procedures.
  • Male patients or non-pregnant, non-nursing female patients 12 to 65 years old, inclusive, at the time of informed consent/assent.
  • Have at least a 6-month history of AD prior to the Screening Visit, and no significant AD flares for the 4 weeks prior to the Screening Visit.

Exclusion

  • Unstable course of AD (spontaneously improving or rapidly deteriorating) based on the patient history or as determined by the investigator during the Screening Period.
  • Concomitant skin disease or clinically infected AD or presence of other skin disease in the area to be dosed that may interfere with study assessments.
  • Female patients who are pregnant, nursing, or planning to become pregnant during the study.

Key Trial Info

Start Date :

May 11 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 14 2023

Estimated Enrollment :

250 Patients enrolled

Trial Details

Trial ID

NCT05432596

Start Date

May 11 2022

End Date

November 14 2023

Last Update

October 26 2024

Active Locations (32)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 8 (32 locations)

1

Aclaris Investigational Site

Birmingham, Alabama, United States, 35244

2

Aclaris Investigational Site

Scottsdale, Arizona, United States, 85255

3

Aclaris Investigational Site

Bryant, Arkansas, United States, 72022

4

Aclaris Investigational Site

North Little Rock, Arkansas, United States, 72117