Status:
UNKNOWN
The Relationship Between Obstructive Sleep Apnea and Alzheimer's Disease: Evidence and Effectiveness
Lead Sponsor:
Chang Gung Memorial Hospital
Conditions:
Obstructive Sleep Apnea of Adult
Mild Cognitive Impairment
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
The research plan to enroll 15 simple snoring patients (apnea/hypopnea \<5, control group), 30 severe OSA patients (apnea/hypopnea \>30, treatment group), and 15 mild cognitive impairment patients (co...
Detailed Description
Obstructive sleep apnea and Alzheimer's disease are both highly prevalent and age-related chronic disease with significant impacts on global public health. The link between OSA and AD showed an inter-...
Eligibility Criteria
Inclusion
- age \>50 years
- control group, AHI\<5 (n=15)
- treatment group, AHI\>30 (n=30)
- Comparative group, mild cognitive impairment (n=15)
Exclusion
- The exclusion criteria were definite neurologic disorders affecting brain structure (e.g., stroke, traumatic head injury or epilepsy), unstable medical diseases involving the heart, lungs, liver or kidneys, chronic insomnia, allergic rhinitis/paranasal sinusitis and alcohol or substance abuse/dependence currently or in the past one year.
Key Trial Info
Start Date :
November 3 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2022
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05433883
Start Date
November 3 2020
End Date
October 1 2022
Last Update
June 27 2022
Active Locations (1)
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1
Chang Gung Memorial Hospital
Taoyuan District, Taiwan, 333