Status:
COMPLETED
Evaluation of Biomarkers Levels in Gingival Crevicular Fluid, Saliva and Serum for Different Periodontal Diseases
Lead Sponsor:
Akdeniz University
Conditions:
Mouth Diseases
Periodontal Inflammation
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The aim of this study is; detection of interleukin(IL)-38, IL-36 gamma(γ) , IL-17 and matrix metalloproteinase(MMP)-9 levels in gingival crevicular fluid (GCF), saliva and serum samples of periodontal...
Eligibility Criteria
Inclusion
- Systemically healthy (The determination of healthy volunteers will be based on the statements of the patients in the anamnesis. No additional examinations will be made.)
- At least twenty permanent teeth in the mouth
- Non-smoker
- No medication for continuous use
- Those who have not used antibiotics, anti-inflammatory and systemic corticosteroid drugs in the last 6 months.
- Not in pregnancy or lactation period.
- For the periodontitis group that has not received periodontal treatment in the last 6 months
Exclusion
- Any oral or systemic disease
- Regularly using a systemic medication
- During pregnancy or lactation
- Received periodontal treatment within the last 6 months.
- Those who received antibiotic, anti-inflammatory or systemic corticosteroid medication in the last 6 months
- Smokers
Key Trial Info
Start Date :
June 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 11 2021
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT05435131
Start Date
June 1 2020
End Date
January 11 2021
Last Update
July 1 2022
Active Locations (1)
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1
Akdeniz University Faculty of Dentistry
Antalya, Turkey (Türkiye), 07070