Status:
COMPLETED
Comparison of Recovery From General Anesthesia in Remimazolam With Flumazenil vs. Propofol
Lead Sponsor:
Seoul National University Hospital
Conditions:
Recovery
Eligibility:
FEMALE
19+ years
Phase:
NA
Brief Summary
This prospective randomized trial aims to compare recovery time from discontinuation of remimazolam followed by flumazenil administration vs. propofol-based total intravenous anesthesia in patients un...
Detailed Description
Adult patients undergoing breast cancer surgery are randomized to receive either remimazolam with flumazenil or propofol-based total intravenous anesthesia. When the surgery is ended, anesthetic agent...
Eligibility Criteria
Inclusion
- Adult patient, age \>19, scheduled for breast cancer surgery under general anesthesia
Exclusion
- Patients who are not alert before procedure
- Day surgery
- BMI ≥35
- Hemodynamicaly unstable patients before procedure
- Patients with history of neromuscular disease or drug use affecting neuromuscular function.
- Patients with history of adverse reaction of allergic reaction to study drugs
- Patients who are anticipated to be unable to remove supraglottic airway or endotracheal tube due to severe dyspnea or need for mechanical ventilatory support
- Use of sedatives (anxiolytics, psychoactive medication, antidepressants, hypnotics) within 24 h
- Known galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption
- Alcohol or drug dependence
- Organic brain disorder
- Patients with hypersensitive to beans or peanut
- Patients who refuse to participate
Key Trial Info
Start Date :
August 2 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 21 2022
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT05435911
Start Date
August 2 2022
End Date
December 21 2022
Last Update
January 13 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Anesthesiology and Pain Medicine, Seoul National University Hospital
Seoul, South Korea, 03080