Status:

RECRUITING

CLDN18.2 Targeting Nanobody Probe for PET Imaging in Solid Tumors

Lead Sponsor:

Peking University Cancer Hospital & Institute

Conditions:

Solid Tumor

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

The objective of the study is to construct a noninvasive approach 68Ga-ACN376 PET/CT to detect the CLDN18.2 expression of tumor lesions in patients with Solid tumors and to identify patients benefitin...

Eligibility Criteria

Inclusion

  • 1\. Aged \>18 years old; ECOG 0 or 1;
  • 2\. Patients with solid tumors;
  • 3\. Has at least one measurable target lesion according to Response Evaluation Criteria in Solid Tumors (RECIST V1.1);
  • 4\. life expectancy \>=12 weeks.

Exclusion

  • 1\. Significant hepatic or renal dysfunction;
  • 2\. Is pregnant or ready to pregnant;
  • 3\. Cannot keep their states for half an hour;
  • 4\. Refusal to join the clinical study;
  • 5\. Suffering from claustrophobia or other mental diseases;
  • 6\. Any other situation that researchers think it is not suitable to participate in the experiment.

Key Trial Info

Start Date :

June 23 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2024

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT05436093

Start Date

June 23 2022

End Date

December 1 2024

Last Update

January 25 2024

Active Locations (1)

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Beijing cancer hospital

Beijing, Beijing Municipality, China, 100142