Status:
RECRUITING
Oral Health and Wilson's Disease: SOMAWI
Lead Sponsor:
Fondation Ophtalmologique Adolphe de Rothschild
Conditions:
Wilson Disease
Eligibility:
All Genders
18+ years
Brief Summary
Patients with Wilson disease have poorer dental and periodontal health and a have lower oral quality of life than control patients. Patients with a neurological form would also more frequently present...
Detailed Description
The comparaison between the three groups is based on evaluation criteria wich is CAOD index of caries severity (developed by Klein and Palmer in 1940) counting the number of permanent teeth with carie...
Eligibility Criteria
Inclusion Criteria:
- Express consent to participate in the study
- Member of or beneficiary of a social security scheme
- For cases: Affected by Wilson's disease
- For controls: Benefiting from a first routine dental consultation with dental panoramic imaging, outside of an emergency context or treatment follow-up/maintenance
Exclusion Criteria:
-
Patient benefiting from a legal protection measure
-
Pregnant or breastfeeding women
-
Severe psychiatric disorders with behavioral disorders
-
For cases:
- hepatic or neurological decompensation
- liver transplant patient
-
For witnesses:
- Patient with hepatic or neurological disease
- Patient taking dietary supplements enriched with copper or zinc or zinc supplementation
- Patient wearing removable prostheses with zinc-enriched prosthetic adhesives (Fixodent ProPlus®)
Key Trial Info
Start Date :
May 17 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT05444127
Start Date
May 17 2023
End Date
October 1 2026
Last Update
December 17 2025
Active Locations (3)
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1
Hopital Charles Foix
Ivry-sur-Seine, France, 94200
2
Hôpital Charles Foix
Ivry-sur-Seine, France, 94200
3
Fondation Adolphe de Rothschild
Paris, France, 75019