Status:

RECRUITING

Oral Health and Wilson's Disease: SOMAWI

Lead Sponsor:

Fondation Ophtalmologique Adolphe de Rothschild

Conditions:

Wilson Disease

Eligibility:

All Genders

18+ years

Brief Summary

Patients with Wilson disease have poorer dental and periodontal health and a have lower oral quality of life than control patients. Patients with a neurological form would also more frequently present...

Detailed Description

The comparaison between the three groups is based on evaluation criteria wich is CAOD index of caries severity (developed by Klein and Palmer in 1940) counting the number of permanent teeth with carie...

Eligibility Criteria

Inclusion Criteria:

  • Express consent to participate in the study
  • Member of or beneficiary of a social security scheme
  • For cases: Affected by Wilson's disease
  • For controls: Benefiting from a first routine dental consultation with dental panoramic imaging, outside of an emergency context or treatment follow-up/maintenance

Exclusion Criteria:

  • Patient benefiting from a legal protection measure

  • Pregnant or breastfeeding women

  • Severe psychiatric disorders with behavioral disorders

  • For cases:

    • hepatic or neurological decompensation
    • liver transplant patient
  • For witnesses:

    • Patient with hepatic or neurological disease
    • Patient taking dietary supplements enriched with copper or zinc or zinc supplementation
    • Patient wearing removable prostheses with zinc-enriched prosthetic adhesives (Fixodent ProPlus®)

Key Trial Info

Start Date :

May 17 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 1 2026

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT05444127

Start Date

May 17 2023

End Date

October 1 2026

Last Update

December 17 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Hopital Charles Foix

Ivry-sur-Seine, France, 94200

2

Hôpital Charles Foix

Ivry-sur-Seine, France, 94200

3

Fondation Adolphe de Rothschild

Paris, France, 75019