Status:

RECRUITING

Brain Health With Inner Engineering Meditation

Lead Sponsor:

Beth Israel Deaconess Medical Center

Conditions:

Meditation

Brain; Agenesis

Eligibility:

All Genders

20-65 years

Phase:

NA

Brief Summary

This study will explore whether a 21-minute meditation practice called Shambhavi Mahamudra Kriya leads to changes in brain health and explore how it affects cognitive and physiological function.

Detailed Description

Meditation has been linked to improved brain health and lower brain age. Brain age has been successfully estimated from structural MRI and more recently, EEG Sleep data using Brain Age Index (BAI) der...

Eligibility Criteria

Inclusion Criteria:

  • Individuals between the ages of 20-65 years.
  • Subjects will be required to be able to understand study instructions and provide informed consent.
  • Currently residing in Massachusetts.

Exclusion Criteria:

  • Non-English Speaking. (Justification: Meditation and cognitive assessment instruments are not validated in a sufficient range of languages, and the research team lacks polylingual capabilities or the financial resources to hire interpreters for the duration of all proposed assessments.)
  • Practicing meditation regularly for the past 6 months (3 or more times per week of practice regularly for the past 6 month).
  • History of psychiatric illness such as severe anxiety, severe depression, Schizophrenia or bipolar disorder.
  • History of any form of cognitive decline or neurological conditions such as dementia, Parkinson's disease, Alzheimer's disease, Huntington's disease, brain tumors, brain surgery.
  • Current use of cognition enhancing drugs
  • Current management for chronic pain.
  • History (within the last 5 years) of stroke/aneurysm.
  • Active history (within the last 5 years) of alcohol or drug abuse (> 10 drinks per week).
  • Current pregnancy or planning to become pregnant in the next 6 months.
  • Currently enrolled in another interventional study that could impact the primary outcome, as determined by the PI.
  • Educational attainment below high school level or equivalent.
  • Significant visual impairment.

Women of childbearing potential will be included as the intervention and the procedures in the study have minimal risks. There will be no enrollment exclusions based on sex, racial or ethnic factors.

If a woman becomes pregnant during the course of the study and is willing to stay as a subject, MRI will not be conducted.

Key Trial Info

Start Date :

January 6 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT05455814

Start Date

January 6 2023

End Date

December 1 2025

Last Update

September 29 2025

Active Locations (1)

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1

Beth Israel Deaconess Medical Centre

Boston, Massachusetts, United States, 02115