Status:

RECRUITING

A Multicentre French Prospective Study of Children With Food Protein Induced Enterocolitis Syndrome in Its Acute Form

Lead Sponsor:

Fondation Lenval

Conditions:

Food Protein Induced Enterocolitis Syndrome (FPIES)

Eligibility:

All Genders

Up to 17 years

Phase:

NA

Brief Summary

Food protein induced enterocolitis syndrome (FPIES), is a non-IgE mediated food allergy (FA) which seems to expand, and occurring in infancy. This disease is usually unknown by clinicians. In 2017, an...

Detailed Description

Food protein induced enterocolitis syndrome (FPIES), is a non-IgE mediated food allergy (FA) which seems to expand, and occurring in infancy. Prevalence of FPIES is unknown. In 2011, Katz published cu...

Eligibility Criteria

Inclusion Criteria:

  • age from 0 to 17 years old,
  • seen in allergologist visit for acute FPIES, due to history of suggestive clinical symptoms, confirmed by the criteria published in 2017 in the JACI (Nowak-Wegrzyn et al, JACI 2017), or by an oral food challenge for diagnosis in the absence of the requested clinical criteria,
  • affiliated to social security (public healthcare system)
  • signed consent of one of the parents or the holder of parental authority

Exclusion Criteria:

  • Associated pathology that may contraindicate OFC at the discretion of the investigating physician. In particular justifying permanent treatment with a beta-blocker or an angiotensin-converting enzyme inhibitor.

Key Trial Info

Start Date :

March 31 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2028

Estimated Enrollment :

600 Patients enrolled

Trial Details

Trial ID

NCT05528900

Start Date

March 31 2023

End Date

October 1 2028

Last Update

September 29 2023

Active Locations (19)

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Page 1 of 5 (19 locations)

1

Chu Angers

Angers, France

2

Chi Robert Ballanger

Aulnay-sous-Bois, France

3

Chu Clermont-Ferrand

Clermont-Ferrand, France

4

Hopital Civils de Colmar

Colmar, France