Status:

RECRUITING

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

Lead Sponsor:

InSightec

Conditions:

Movement Disorders

Neurology

Eligibility:

All Genders

30-99 years

Brief Summary

This registry is a prospective, multicenter, international, single arm, observational post-approval registry with follow-up at 3, 6, and 12 months, and annually for 5 years. The proposed registry will...

Detailed Description

This is a post-approval registry which is required by of the approval under PMA P150038/S014 for the Exablate® Model 4000 (Exablate Neuro) Type 1.0 and Type 1.1 for unilateral pallidotomy in the treat...

Eligibility Criteria

Inclusion Criteria:

  • Men and women, age 30 years and older.
  • Subject undergoing a planned an Exablate procedure for their Parkinson's Disease with Motor Complications per local institution standard of care.
  • Subject is willing to cooperate with the Registry requirements including compliance with the regimen and completion of all Registry visits.
  • Subject has signed and received a copy of the approved informed consent form.

Exclusion Criteria:

  • Subject does not agree to participate or is unlikely to participate for the entirety of the Registry.

Key Trial Info

Start Date :

January 23 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 31 2029

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05539196

Start Date

January 23 2023

End Date

July 31 2029

Last Update

March 20 2026

Active Locations (5)

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Page 1 of 2 (5 locations)

1

University of Maryland, Baltimore

Baltimore, Maryland, United States, 21201

2

Weill Cornell Medicine

New York, New York, United States, 10065

3

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19106

4

University of Texas Southwestern Medical Center

Dallas, Texas, United States, 75390