Status:

RECRUITING

A Behavioural Weight Loss Intervention Delivered in Cardiac Rehabilitation for Patients With Atrial Fibrillation and Obesity

Lead Sponsor:

University of Calgary

Collaborating Sponsors:

Alberta Health services

University of British Columbia

Conditions:

Atrial Fibrillation

Obesity

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

One-in-four Canadians will be diagnosed with an abnormal heart rhythm called atrial fibrillation (AF) in their lifetime. This is expected to double by 2050, owing to an aging population and increased ...

Detailed Description

Background: One-in-four Canadians will develop atrial fibrillation (AF), increasing risk of heart failure and stroke. Obesity (i.e., BMI ≥30 kg/m2) represents a strong, independent risk factor for inc...

Eligibility Criteria

Inclusion

  • Adults of age ≥18 years
  • Symptomatic paroxysmal or persistent atrial fibrillation or atrial flutter
  • Classified as obese (BMI ≥30 kg/m2)
  • Have a sedentary lifestyle (not currently meeting basic physical activity targets of ≥150 minutes/week)
  • Ability to speak and write in English
  • Willingness to be referred to a behavioural weight loss treatment (BWLT)
  • At least one of the following: obstructive sleep apnea, diabetes, hypertension, heart failure, dyslipidemia, CAD, peripheral artery, or cerebrovascular disease.

Exclusion

  • Longstanding-persistent (defined as ≥ 3 years continuous AF) or permanent AF
  • Uncontrolled coronary artery disease
  • Completed a CR program within the previous year
  • Currently enrolled in a structured behavioural weight loss program
  • Currently scheduled to receive catheter ablation in AF
  • Currently taking GLP-1 receptor agonist or
  • Received bariatric surgery in the previous year prior to enrollment OR scheduled for bariatric surgery during the study period.

Key Trial Info

Start Date :

June 22 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 30 2026

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT05600829

Start Date

June 22 2023

End Date

March 30 2026

Last Update

April 25 2024

Active Locations (1)

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Behavioural Medicine Lab

Calgary, Alberta, Canada