Status:

RECRUITING

A Longitudinal Study to Identify Mechanisms of Menopause on Cardiovascular Disease Risk

Lead Sponsor:

University of Copenhagen

Conditions:

Menopause

Cardiovascular Diseases

Eligibility:

FEMALE

40-61 years

Brief Summary

With the cessation of estrogen production at menopause, the risk of cardiovascular disease like arthrosclerosis, myocardial infarction and stroke increases dramatically. Physical activity is the singl...

Eligibility Criteria

Inclusion Criteria:

  • Normal ECG
  • Regular menstruation

Exclusion Criteria:

  • Participation in other clinical projects
  • Smokes or has smoked within the last 10 years
  • On hormone therapy
  • Has chronic diseases that are not expected, cf. the groups sought. Including heart problems, atrial fibrillation, cancer, immune diseases and previous strokes with functionally significant sequelae
  • Being treated with oral steroids
  • Has alcohol / drug abuse or is being treated with disulfiram (Antabus)
  • Is unable to understand the contents of the document with informed consent or the experimental procedures
  • Pregnancy or breastfeeding
  • Systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg
  • ovariectomy
  • BMI>28

Key Trial Info

Start Date :

December 16 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 1 2045

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT05647876

Start Date

December 16 2022

End Date

August 1 2045

Last Update

May 10 2023

Active Locations (1)

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Deparment of Nutrition, Exercise and Sports

Copenhagen, Denmark, 2100